To help you set your fantasy football lineups and to avoid starting a player who won't be in the lineup, we'll post fantasy-relevant updates and analysis here as NFL teams release their inactives, typically about 90 minutes before kickoff. Any rankings cited in this column come from our ESPN Fantasy staff ranks.
Refresh often for the latest information.
Sunday night game
Los Angeles Rams
Micah Kiser, LB, LAR: Groin -- Active
San Francisco 49ers
Kwon Alexander, LB, SF: Ankle -- OUT
Emmanuel Moseley, CB, SF: Concussion -- Active
Dante Pettis, WR, SF: OUT
C.J. Beathard, QB, SF: OUT
Official Sunday inactives should begin coming in at approximately 11:30 a.m. ET for the early games and 2:30 p.m. ET for the late games.
4 p.m. ET games
Offense
Sam Darnold, QB, NYJ: Shoulder -- Inactive
Impact: Joe Flacco will start again for the Jets. He should not start for you.
Breshad Perriman, WR, NYJ: Ankle -- Active
Impact: Even with bye weeks in full swing, look elsewhere for fantasy WR options.
Leonard Fournette, RB, TB: Ankle -- Inactive
Impact: It's all Ronald Jones II in the Buccaneers' backfield. Additionally, wide receivers Chris Godwin and Mike Evans are healthy and will start.
Defense
Za'Darius Smith, LB, GB: Ankle -- Active
Rashan Gary, LB, GB: Ankle -- Active
Kevin King, CB, GB: Quad -- Inactive
Shaq Lawson, DE, MIA: Shoulder -- Active
Kyle Van Noy, LB, MIA: Groin -- Inactive
Quinnen Williams, DE, NYJ: Hamstring -- Active
Bless Austin, CB, NYJ: Calf -- Active
Carlton Davis, CB, TB: Abdomen -- Active
1 p.m. ET games
Offense
Chris Moore, WR, BAL: Thigh -- Inactive
Impact: Boykin, who is active, could have a solid day as Baltimore's No. 3 WR ...
Miles Boykin, WR, BAL: Thigh -- Active
Impact: ... with Devin Duvernay and James Proche II as roll-the-dice options.
Curtis Samuel, WR, CAR: Knee -- Inactive
Impact: Seth Roberts could have a nice day as his replacement.
Auden Tate, WR, CIN: Shoulder -- Inactive
Impact: A.J. Green will be able to play. The rise of Tee Higgins has made Tate somewhat fantasy-irrelevant.
Baker Mayfield, QB, CLE: Chest -- Active
Impact: Practiced Friday, so no surprise to see him starting. Case Keenum remains the literal just-in-case option.
Odell Beckham Jr., WR, CLE: Illness -- Active
Impact: Was expected to play after recovering from what team is calling a non-COVID-19 illness earlier in the week.
Jarvis Landry, WR, CLE: Ribs -- Active
Impact: Rashard Higgins is on deck if he can't play a full 60 minutes.
Drew Lock, QB, DEN: Shoulder -- Active
Impact: Blake Bortles was released, which was a sign of confidence that Lock would indeed play.
Melvin Gordon III, RB, DEN: Illness -- OUT
Impact: Didn't travel to New England. Phillip Lindsay to handle No. 1 RB workload.
KJ Hamler, WR, DEN: Hamstring -- OUT
Impact: DaeSean Hamilton should be involved in 3-WR sets.
Noah Fant, TE, DEN: Ankle -- OUT
Impact: Nick Vannett/Jake Butt to share the TE workload in Denver.
Jordan Wilkins, RB, IND: Calf -- Active
Impact: Very little practice this week. Nyheim Hines could get a few extra touches.
Mo Alie-Cox, TE, IND: Knee -- OUT
Impact: Trey Burton has potential for a good number of TE targets.
DJ Chark Jr., WR, JAX: Ankle -- Active
Impact: This was a game-time call, so proceed with caution. Laviska Shenault Jr. has played very well in recent weeks.
Tyler Eifert, TE, JAX: Neck -- Active
Impact: Missed two days of practice, so James O'Shaughnessy may still see a lot of snaps.
Dalvin Cook, RB, MIN: Groin -- OUT
Impact: If you had Alexander Mattison as an insurance policy, now's the time to cash in.
Julian Edelman, WR, NE: Knee -- Active
Impact: No surprise to see him ready to go. Cam Newton may return to the huddle this week to throw passes Edelman's way.
Sony Michel, RB, NE: Illness/COVID -- OUT
Impact: Michel (already on IR) has now been placed on the reserve/COVID-19 list. Rex Burkhead/James White/Damien Harris to split the RB load.
Darius Slayton, WR, NYG: Foot -- Active
Impact: Quite frankly, there's nothing behind him on the Giants' WR depth chart.
DeSean Jackson, WR, PHI: Hamstring -- OUT
Impact: Travis Fulgham has the opportunity to attempt an encore of last week's strong showing.
Alshon Jeffery, WR, PHI: Foot -- OUT
Impact: John Hightower/Greg Ward should both see some looks.
Diontae Johnson, WR, PIT: Back -- OUT
Impact: Week 5 fantasy darling Chase Claypool will get a chance to prove that it wasn't a fluke.
Defense
Takkarist McKinley, DE, ATL: Groin -- OUT
Derek Wolfe, DE, BAL: Neck -- Inactive
Brandon Williams, DT, BAL: Illness/COVID -- OUT
Marcus Peters, CB, BAL: Thigh -- Active
Zach Kerr, DT, CAR: Toe -- Active
Donte Jackson, CB, CAR: Toe -- Active
Mackensie Alexander, CB, CIN: Ribs -- Active
Olivier Vernon, DE, CLE: Groin -- Active
Larry Ogunjobi, DT, CLE: Abdomen -- Active
Karl Joseph, S, CLE: Hamstring -- OUT
Jeremiah Attaochu, DE, DEN: Quad -- OUT
Mike Purcell, DT, DEN: Knee -- Active
Justin Houston, DE, IND: Hip -- Active
Denico Autry, DT, IND: Ankle -- Active
Darius Leonard, LB, IND: Groin -- Inactive
Abry Jones, DT, JAX: Ankle -- Inactive
Josh Allen, DE, JAX: Knee -- Inactive
Adam Butler, DT, NE: Shoulder -- Active
Dexter Lawrence, DT, NYG: Knee -- Active
Lorenzo Carter, LB, NYG: Achilles -- OUT
Duke Riley, LB, PHI: Ribs -- OUT
Avonte Maddox, CB, PHI: Ankle -- OUT
Marcus Epps, S, PHI: Ribs -- OUT
Darius Slay, CB, PHI: Concussion -- Active
DaQuan Jones, DT, TEN: Foot -- Active