Find out who is missing through injury, who's in a race against time to prove their fitness and who has been ruled out through suspension for the next round of LaLiga fixtures.
And as you plan your fantasy team for the next gameweek, check out the predicted XIs for all 20 clubs.
Positions: Goalkeeper (GK), Defender (D), Left-back (LB), Right-back (RB), Centre-back (CB), Midfielder (M), Defensive midfield (DM), Central midfield (CM), Left midfield (LM), Right midfield (RM), Attacking midfield (AM), Left winger (LW), Right winger (RW), Forward (F), Left forward (FWL), Right forward (FWR), Striker (ST)
(All predicted XIs and injury news powered by Rotowire and subject to updates.)
Alavés v Mallorca
Mendizorroza, Vitoria-Gasteiz
Friday, 4 p.m. ET/ 8 p.m. UK
Latest Alavés team news
Expected Lineup:
GK Antonio Sivera
LB Manu Sánchez | CB Abdel Abqar | CB Aleksander Sedlar | RB Nahuel Tenaglia
CM Ander Guevara | CM Joan Jordán
LW Carlos Martín | AM Jon Guridi | RW Carlos Vicente
ST Toni Martínez
Injury/suspension updates:
Hugo Novoa, M, abdomen, OUT, estimated return Nov. 23
Latest Mallorca team news
Expected Lineup:
GK Dominik Greif
LB Johan Mojica | CB Antonio Raíllo | CB Martin Valjent | RB Pablo Maffeo
LM Sergi Darder | CM Omar Mascarell | CM Manu Morlanes | RM Robert Navarro
ST Cyle Larin | ST Vedat Muriqi
Injury/suspension updates:
Takuma Asano, F, strain, OUT, estimated return Nov. 23
Samu Costa, M, suspension, due back Nov. 23
Javier Exposito, F/M, thigh, OUT, estimated return Nov. 23
Osasuna v Real Valladolid
El Sadar, Pamplona
Saturday, 9 a.m. ET / 1 p.m. UK
Latest Osasuna team news
Expected Lineup:
GK Sergio Herrera
LB Juan Cruz | CB Flavien-Enzo Boyomo | CB Alejandro Catena | RB Jesús Areso
CM Jon Moncayola | CM Aimar Oroz | CM Lucas Torró
FWL Bryan Zaragoza | ST Ante Budimir | FWR Rubén García
Injury/suspension updates:
Rubén García, F/M, undisclosed, DOUBT
Latest Real Valladolid team news
Expected Lineup:
GK Karl Hein
LB Lucas Rosa | CB Javi Sánchez | CB David Torres | RB Luis Perez
DM Mario Martín | DM Eray Cömert
LW Raúl Moro | AM Selim Amallah | RW Anuar
ST Mamadou Diallo
Injury/suspension updates:
César De la Hoz, M, back, DOUBT
Cenk Özkacar, D, hamstring, DOUBT
Girona v Leganés
Municipal de Montilivi, Girona
Saturday, 11:15 a.m. ET / 3:15 p.m. UK
Latest Girona team news
Expected Lineup:
GK Paulo Gazzaniga
CB Daley Blind | CB Ladislav Krejcí | CB David López
LM Miguel Gutiérrez | CM Yangel Herrera | CM Donny van de Beek | RM Arnau Martínez
AM Gabriel Misehouy
ST Bojan Miovski | ST Arnaut Danjuma
Injury/suspension updates:
Ricard Artero, M, ankle, OUT, estimated return Nov. 24
Yáser Asprilla, M, ankle, DOUBT
Arnaut Danjuma, F/M, undisclosed, DOUBT
Jastin Garcia, F/M, shoulder, DOUBT
Pau López, G, hand, OUT, estimated return Nov. 24
Portu, F/M, ankle, DOUBT
Ivan Martin, M, groin, OUT, estimated return Nov. 23
Oriol Romeu, M, hamstring, OUT, estimated return Nov. 24
Abel Ruiz, F, groin, DOUBT
Jhon Solis, M, thigh, OUT, estimated return Nov. 24
Latest Leganés team news
Expected Lineup:
GK Marko Dmitrovic
CB Sergio González | CB Matija Nastasic | CB Renato Tapia
LM Enric Franquesa | CM Darko Brasanac | CM Seydouba Cissé | CM Yvan Neyou | RM Adrià Altimira
ST Sébastien Haller | ST Juan Cruz
Injury/suspension updates:
Diego Garcia, F, undisclosed, DOUBT
Naim García, F/M, undisclosed, DOUBT
Sébastien Haller, F, thigh, DOUBT
Dani Raba, F, undisclosed, DOUBT
Jorge Saenz, D, undisclosed, DOUBT
Atlético Madrid v Las Palmas
Riyadh Air Metropolitano, Madrid
Sunday, 8 a.m. ET / 12 p.m. UK
Latest Atlético Madrid team news
Expected Lineup:
GK Jan Oblak
LB Javi Galán | CB José María Giménez | CB Axel Witsel | RB Nahuel Molina
LM Julián Álvarez | CM Rodrigo De Paul | CM Koke | RM Ángel Correa
ST Alexander Sorloth | ST Antoine Griezmann
Injury/suspension updates:
César Azpilicueta, D, leg, DOUBT
Pablo Barrios, M, leg, DOUBT
Robin Le Normand, D, concussion, DOUBT
Clément Lenglet, D, ankle, OUT, estimated return Nov. 23
Marcos Llorente, M/D, thigh, DOUBT
Latest Las Palmas team news
Expected Lineup:
GK Jasper Cillessen
LB Álex Muñoz | CB Scott McKenna | CB Álex Suárez | RB Viti
DM José Campaña | DM Dário Essugo
LW Alberto Moleiro | AM Kirian Rodríguez | RW Adnan Januzaj
ST Fábio Silva
Injury/suspension updates:
Marvin, M/D, hamstring, DOUBT
Iván Gil, F/M, coach's decision, DOUBT
Barcelona v Espanyol
Estadi Olímpic Lluís Companys, Barcelona
Sunday, 10:15 a.m. ET / 3:15 p.m. UK
Latest Barcelona team news
Expected Lineup:
GK Iñaki Peña
LB Alejandro Balde | CB Iñigo Martínez | CB Pau Cubarsí | RB Jules Koundé
DM Marc Casadó | DM Pedri
LW Raphinha | AM Dani Olmo | RW Lamine Yamal
ST Robert Lewandowski
Injury/suspension updates:
Ronald Araújo, D, hamstring, OUT, estimated return Nov. 24
Marc Bernal, M/D, knee, OUT, estimated return Sep. 1
Andreas Christensen, D, achilles, OUT, estimated return Nov. 26
Eric García, D, groin, DOUBT
Marc-André ter Stegen, G, knee, OUT, estimated return Apr. 6
Ferran Torres, F, hamstring, OUT, estimated return Dec. 15
Latest Espanyol team news
Expected Lineup:
GK Joan García
LB Carlos Romero | CB Leandro Cabrera | CB Marash Kumbulla | CB Brian Oliván | RB Omar El Hilali
LM Javi Puado | CM Alex Král | CM Pol Lozano | RM Jofre Carreras
ST Alejo Veliz
Injury/suspension updates:
Fernando Calero, D, achilles, DOUBT
Edu Exposito, M, knee, DOUBT
Sevilla v Real Sociedad
Ramón Sánchez-Pizjuán, Sevilla
Sunday, 12:30 p.m. ET / 5:30 p.m. UK
Latest Sevilla team news
Expected Lineup:
GK Álvaro Fernández
LB Adrià Pedrosa | CB Marcão | CB Kike Salas | RB José Ángel Carmona
DM Nemanja Gudelj
CM Albert Sambi Lokonga | CM Juanlu
FWL Stanis Idumbo | ST Isaac | FWR Dodi Lukebakio
Injury/suspension updates:
Loïc Badé, D, thigh, OUT, estimated return Nov. 24
Chidera Ejuke, F, hamstring, OUT, estimated return Dec. 1
Suso, F/M, groin, OUT, estimated return Nov. 24
Tanguy Nianzou, D, hamstring, OUT, estimated return Nov. 24
Saúl Ñíguez, M, undisclosed, DOUBT
Ørjan Nyland, G, knee, OUT, estimated return Dec. 1
Latest Real Sociedad team news
Expected Lineup:
GK Alex Remiro
LB Sergio Gómez | CB Nayef Aguerd | CB Igor Zubeldia | RB Jon Aramburu
DM Martín Zubimendi
LM Ander Barrenetxea | CM Brais Méndez | CM Luka Sucic | RM Takefusa Kubo
ST Mikel Oyarzabal
Injury/suspension updates:
Pablo Marín, M, undisclosed, DOUBT
Hamari Traoré, D, knee, OUT, estimated return May. 4
Arsen Zakharyan, M, ankle, DOUBT
Athletic Club v Real Betis
San Mamés, Bilbao
Sunday, 3 p.m. ET / 8 p.m. UK
Latest Athletic Club team news
Expected Lineup:
GK Julen Agirrezabala
LB Yuri Berchiche | CB Unai Núñez | CB Dani Vivian | RB Óscar de Marcos
DM Mikel Jauregizar | DM Iñigo Ruiz de Galarreta
LW Nico Williams | AM Álex Berenguer | RW Iñaki Williams
ST Gorka Guruzeta
Injury/suspension updates:
Unai Simón, G, wrist, OUT, estimated return Dec. 15
Latest Real Betis team news
Expected Lineup:
GK Rui Silva
LB Romain Perraud | CB Marc Bartra | CB Diego Llorente | RB Héctor Bellerín
LM Abde Ezzalzouli | CM Sergi Altimira | CM Johnny Cardoso | RM Pablo Fornals
ST Chimy Ávila | ST Vitor Roque
Injury/suspension updates:
Isco, F/M, leg, OUT, estimated return Dec. 1
William Carvalho, M, achilles, OUT, estimated return May. 4
Giovani Lo Celso, F/M, thigh, DOUBT
Marc Roca, M, ankle, DOUBT
Aitor Ruibal, D, thigh, OUT, estimated return Nov. 23
Celta Vigo v Getafe
Estadio Abanca-Balaídos, Vigo
Monday, 3 p.m. ET / 8 p.m. UK
Latest Celta Vigo team news
Expected Lineup:
GK Vicente Guaita
CB Javier Manquillo | CB Carl Starfelt | CB Marcos Alonso
LM Hugo Álvarez | CM Fran Beltrán | CM Hugo Sotelo | RM Óscar Mingueza
FWL Williot Swedberg | ST Borja Iglesias | FWR Iago Aspas
Injury/suspension updates:
Luca de la Torre, M, ankle, DOUBT
Jailson, M, groin, DOUBT
Latest Getafe team news
Expected Lineup:
GK David Soria
LB Diego Rico | CB Omar Alderete | CB Djene Dakonam | RB Juan Iglesias
LM Álex Sola | CM Mauro Arambarri | CM Luis Milla | RM Carles Pérez
ST Bertug Yildirim | ST Christantus Uche
Injury/suspension updates:
Borja Mayoral, F, strain, DOUBT