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NFL Insiders Predict: Upsets, fantasy flops, more for Week 2

Now that we've finally had real, regular-season football, our NFL Insiders take a crack at picking looming upsets, fantasy flops, bounce-back players and much more headed into Week 2.

What's your biggest upset pick for Week 2?

Matt Bowen, NFL writer: The Falcons are 5.5-point underdogs at Oakland, but Matt Ryan has enough weapons to produce points against a Raiders defense that was just torn up by Drew Brees and the Saints. Sure, Derek Carr is going to make plays against the Atlanta defense, but don't be surprised if the Falcons steal one in a shootout.

Dan Graziano, national NFL insider: The only betting-line upset I picked was the Jaguars over the Chargers, but I don't think that's very exciting or controversial. So I'd like to make the point that the Rams are 3-1 against the Seahawks the past two years and 10-19 against everyone else. No one looked worse than the Rams did in Week 1, but you can be sure Seattle, which has had a miserable time with Jeff Fisher's team in recent years, isn't overlooking them.

Mike Sando, senior NFL writer: The Buccaneers have the weapons to exploit the Cardinals' coverage deficiencies. They also have a fearless quarterback in Jameis Winston. That makes Tampa Bay dangerous even as a 7.5-point underdog. It's a long shot, but so were the Patriots at Arizona last week.