The AFL will experiment with two matches on Friday nights for the first time next season, scheduling marquee fixtures in separate states in Rounds 3 and 8.
The league released Rounds 1 to 9 of the 2022 fixture on Thursday, along with the match-ups for Rounds 10 to 23.
The schedule of matches from Round 10 onwards is floating, to be confirmed after the season begins on March 16.
Melbourne will host the Western Bulldogs at the MCG in a Grand Final rematch to start the season before Carlton and Richmond do battle in the first of five consecutive Thursday night matches in the opening five rounds.
Two Friday night matches have been scheduled to take place at the same time in Round 3, with South Australia's Adelaide-Port Adelaide Showdown overlapping with a Melbourne-Essendon MCG clash.
It will allow the AFLW grand final to be played in clear air the following day, with a window in the twilight slot.
The Friday night experiment will be repeated in Round 8 with Port Adelaide-Bulldogs and Fremantle-North Melbourne matches.
The double-headers in the marquee timeslot will happen for the first time since round 10, 1999.
"It's a trial to see how it performs and I'm sure we'll learn like we have over the last couple of years how that new concept performs and respond accordingly," AFL clubs and broadcasting boss Travis Auld said.
"You'd love every game to have clean air ... but what you do is try and get that over-lap right and so there's not such a big impact.
"There's parts of that game (the Showdown) that will crossover with the next game but that's just something we have to work through."
The Dockers, Hawthorn and Gold Coast -- who all missed the finals in 2021 -- are the only clubs without matches in the marquee Thursday and Friday timeslots over the opening six rounds.
"We begin season 2022 with a renewed level of confidence - taking the learnings of the previous year and focusing on delivering fans another blockbuster schedule of matches," Auld said.
"For supporters it is a chance to get back to doing what we all love, going to the footy with our family and friends.
"On the field, it feels like we are in for another unpredictable season.
"The competitiveness and the ability for any team to win on any day gave us great confidence in the spread of marquee timeslots to begin the season."