Thanksgiving means football and all 32 teams will be in action this week a full course of 11 games on Sunday.
Sunday afternoon's action will be highlighted by the 4:25 p.m. ET matchup between the Philadelphia Eagles and Baltimore Ravens, which opened with the biggest total of the week (50.5) and which sees the Ravens favored by 2 1/2 points.
The prime-time games will feature the San Francisco 49ers at the Buffalo Bills on Sunday night, followed by the Cleveland Browns and Denver Broncos on Monday Night Football.
Here's a look at all 16 games on the Week 13 slate. Football Power Index (FPI) by ESPN Analytics. Odds current as of publication time. For most current odds go to ESPN BET
Pittsburgh Steelers vs. Cincinnati Bengals -3
Sunday, 1 p.m. ET, CBS
Money Line: Steelers (+130) ; Bengals (-150)
Total: 48.5; Opened: 46.5
FPI favorite: Bengals by 0.3, 51.2% to win outright
Los Angeles Chargers -2.5 vs. Atlanta Falcons
Sunday, 1 p.m. ET, CBS
Money Line: Chargers (-130) ; Falcons (+110)
Total: 48.5; Opened: 47.5
FPI favorite: Chargers by 0.4, 51.4% to win outright
Indianapolis Colts -2.5 vs. New England Patriots
Sunday, 1 p.m. ET, CBS
Money Line: Colts (-145) ; Patriots (+125)
Total: 42.5; Opened: 42.5
FPI favorite: Colts by 4.4, 61.6% to win outright
Tennessee Titans vs. Washington Commanders -5.5
Sunday, 1 p.m. ET, CBS
Money Line: Titans (+210) ; Commanders (-250)
Total: 44.5; Opened: 44.5
FPI favorite: Commanders by 6.2, 66.4% to win outright
Seattle Seahawks -2 vs. New York Jets
Sunday, 1 p.m. ET, FOX
Money Line: Seahawks (-125) ; Jets (+105)
Total: 41.5; Opened: 41.5
FPI favorite: Jets by 1.9, 53.8% to win outright
Houston Texans -4 vs. Jacksonville Jaguars
Sunday, 1 p.m. ET, FOX
Line movement: Opened Texans -6.5
Money Line: Texans (-195) ; Jaguars (+165)
Total: 43.5; Opened: 42.5
FPI favorite: Texans by 5.8, 64.5% to win outright
Arizona Cardinals vs. Minnesota Vikings -3.5
Sunday, 1 p.m. ET, FOX
Money Line: Cardinals (+150) ; Vikings (-175)
Total: 45.5; Opened: 46.5
FPI favorite: Vikings by 3.3, 58.7% to win outright
Tampa Bay Buccaneers -6 vs. Carolina Panthers
Sunday, 4:05 p.m. ET, FOX
Money Line: Buccaneers (-260) ; Panthers (+215)
Total: 46.5; Opened: 46.5
FPI favorite: Buccaneers by 7.6, 68.9% to win outright
Los Angeles Rams -2.5 vs. New Orleans Saints
Sunday, 4:05 p.m. ET, FOX
Money Line: Rams (-145) ; Saints (+125)
Total: 48.5; Opened: 46.5
FPI favorite: Saints by 0.8, 51.8% to win outright
Philadelphia Eagles vs. Baltimore Ravens -3
Sunday, 4:25 p.m. ET, CBS
Money Line: Eagles (+140) ; Ravens (-165)
Total: 51.5; Opened: 50.5
FPI favorite: Ravens by 2.9, 58.5% to win outright
San Francisco 49ers vs. Buffalo Bills -7
Sunday, 8:20 p.m. ET, NBC, Peacock
Money Line: 49ers (+260) ; Bills (-320)
Total: 44.5; Opened: 45.5
FPI favorite: Bills by 4.1, 61.5% to win outright
Cleveland Browns vs. Denver Broncos -5.5
Monday, 8:15 p.m. ET, ESPN
Money Line: Browns (+215) ; Broncos (-260)
Total: 41.5; Opened: 41.5
FPI favorite: Broncos by 0.7, 52% to win outright