Sony Michel rushed for 121 yards and a touchdown in the victory.
Wide receiver Odell Beckham Jr. also was active and a touchdown reception in the win. Like Henderson, he was listed as questionable. Beckham has a hip injury.
Running back James Robinson is active for the Jaguars. He had been listed as questionable because of heel and knee injuries. Robinson has been hobbled for weeks with the injuries but was feeling better Saturday.
Henderson, the Rams' top running back, has rushed for 648 yards and five touchdowns this season.