The British & Irish Lions tour suffered a blow on Tuesday with the postponement of their weekend game in Pretoria amid an outbreak of COVID-19 cases in South African rugby that highlighted the growing third wave of infections in the country.
The Lions were to play the Bulls at Loftus Versfeld on Saturday but four of the local players, plus one official, tested positive and because of their close contact with team mates, all must isolate, leaving the Currie Cup champions unable to field a team, organisers said.
There were also more players who tested positive on Tuesday in the Springbok camp, as the home country prepares for their three tests against the tourists, starting on July 24.
South Africa coach Jacques Nienaber and five other staff members also tested positive, a statement from SA Rugby and the Lions said on Tuesday.
South Africa are due to play Georgia in a second warm-up test in Johannesburg on Friday but that is now in the balance after Georgia also reported four positive cases on Tuesday.
A decision on Friday's test will be made on Wednesday by a medical advisory group set up for the tour to oversee COVID-19 protocols and rule on cases, but it would be a surprise if it went ahead.
The outbreak of cases realises officials' worst fears as South Africa, despite a severe lockdown, grapples with the virus with a record number of 26,000 fresh cases reported at the weekend and hospitals heaving under the strain of infections.
All teams are in bio-secure hotels and supposed to follow strict protocols with regular testing. The Lions said they were being tested four times a week.
"These positive results are a setback and have underlined the danger of transmissibility of the Delta variant," said SA rugby's chief executive officer Jurie Roux.
"The priority is to maintain the integrity of the test series and we will continue to focus on that," he added.
The touring Lions will go ahead with Wednesday's game against the Sharks at Ellis Park with no cases reported in those camps but there will be concern about next week's fixture against South Africa A in Cape Town.
The local players for that game are being drawn from an expansive Springbok squad, which has now had seven positive cases over the last week.
The latest Springbok players to test positive were named as Frans Malherbe, Marvin Orie, Handre Pollard and Frans Steyn, who all played last Friday when South Africa beat Georgia 40-9 in the first test in Pretoria.
Tour rules allow for postponed matches to be rescheduled, which means there is a chance the Lions could still play the Bulls later in the eight-week tour.
The Lions' schedule has five matches against franchise teams, as well as South Africa A, followed by the three tests on successive Saturdays with no midweek matches once the tests begin.