Detroit Lions veteran defensive end John Cominsky tore the MCL in his right knee at practice Tuesday and now is expected to be out indefinitely, sources told ESPN's Adam Schefter.
Cominsky could be "possibly back for the playoffs" should the Lions advance that far, a source told Schefter.
Cominsky was carted off the field Tuesday, when the team had its second padded practice.
The 6-foot-5, 285-pound Cominsky started all three of Detroit's playoff games after starting 11 of 16 games in the regular season.
He was credited with two quarterback hurries in the postseason, helping the NFC North champion Lions win two playoff games in the same postseason for the first time since 1957, and two sacks in the regular season.
Cominsky had career highs with four sacks and 32 tackles in his first season with the Lions in 2022 after playing for the Atlanta Falcons during his first three years.
Aidan Hutchinson, drafted No. 2 overall in 2022, is Detroit's top defensive end and the team is counting on veteran Marcus Davenport being healthy and productive after signing him to a $10.5 million, one-year contract in the offseason.
The Associated Press contributed to this report.